@UAB

selected publications


Nat. Comm. (2024)

Structural diversity and clustering of bacterial flagellar outer domains

Jessie Lynda Fields, Hua Zhang, Nathan F. Bellis, Holly A. Petersen, Sajal K. Halder, Shane T. Rich-New, Mart Krupovic, Hui Wu, and Fengbin Wang 


JACS (2024)

Cell-Free Nonequilibrium Assembly for Hierarchical Protein/Peptide Nanopillars

Jiaqi Guo, Ayisha Zia, Qianfeng Qiu, Michael Norton, Kangqiang Qiu, Junichi Usuba, Zhiyu Liu, Meihui Yi, Shane T Rich-New, Michael Hagan, Seth Fraden, Grace D Han, Jiajie Diao, Fengbin Wang, Bing Xu


Nat. Comm. (2024)

Two dramatically distinct archaeal type IV pili structures formed by the same pilin

Junfeng Liu, Gunnar N. Eastep, Virginija Cvirkaite-Krupovic, Shane T. Rich-New, Mark A.B. Kreutzberger, Edward H. Egelman, Mart Krupovic, Fengbin Wang


Cell (2023)

Extracellular cytochrome nanowires appear to be ubiquitous in prokaryotes

Diana P. Baquero, Virginija Cvirkaite-Krupovic, Shengen Shawn Hu, Jessie Lynda Fields, Xing Liu, Christopher Rensing, Edward H. Egelman, Mart Krupovic, Fengbin Wang


Nat Nanotech (2023)

Cell spheroid creation by transcytotic intercellular gelation

Jiaqi Guo, Fengbin Wang, Yimeng Huang, Hongjian He, Weiyi Tan, Meihui Yi, Edward H. Egelman, Bing Xu


Chem (2023)

Hierarchical assembly of intrinsically disordered short peptides

Jiaqi Guo, Shane T. Rich-New, Chen Liu, Yimeng Huang, Weiyi Tan, Hongjian He, Meihui Yi, Xixiang Zhang, Edward H. Egelman, Fengbin Wang, and Bing Xu


Brief. Bioinformatics (2023)

Fast and Automated Protein-DNA/RNA Macromolecular Complex Modeling from Cryo-EM Maps

Andrew Nakamura, Hanze Meng, Minglei Zhao, Fengbin Wang, Jie Hou, Renzhi Cao, Dong Si


Trends Microbiol. (2022)

Microbial nanowires: type IV pili or cytochrome filaments?

Fengbin Wang, Lisa Craig, Xing Liu, Christopher Rensing, Edward H. Egelman

Previous to UAB

selected publications


eLife (2022)

Structure of Geobacter OmcZ filaments suggests extracellular cytochrome polymers evolved independently multiple times

Fengbin Wang, Chi Ho Chan, Victor Suciu, Khawla Mustafa, Madeline Ammend, Dong Si, Allon I Hochbaum, Edward H Egelman, Daniel R Bond


Cell (2022)

Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome.

Fengbin Wang, Virginija Cvirkaite-Krupovic, Matthijn Vos, Leticia C Beltran, Mark AB Kreutzberger, Jean-Marie Winter, Zhangli Su, Jun Liu, Stefan Schouten, Mart Krupovic, Edward H Egelman


JACS (2022)

Enzyme Responsive Rigid-Rod Aromatics Target “Undruggable” Phosphatases to Kill Cancer Cells in a Mimetic Bone Microenvironment

Meihui Yi, Fengbin Wang, Weiyi Tan, Jer-Tsong Hsieh, Edward H. Egelman, and Bing Xu


Chem. Rev. (2022)

Cryo-EM of Helical Polymers

Fengbin Wang, Ordy Gnewou, Armin Solemanifar, Vincent P Conticello, Edward H Egelman


Nat. Microbio. (2022)

Cryo-EM structure of an extracellular Geobacter OmcE cytochrome filament reveals tetrahaem packing

Fengbin Wang, Khawla Mustafa, Victor Suciu Zhangli Su, Dong Si, Allon I. Hochbaum, Edward H. Egelman and Daniel R. Bond


PNAS (2022)

Archaeal bundling pili of Pyrobaculum calidifontis reveal similarities between archaeal and bacterial biofilms

Fengbin Wang, Virginija Cvirkaite-Krupovic, Mart Krupovic, and Edward H. Egelmana


BPJ (2022)

DeepTracer ID: De Novo Protein Identification from Cryo-EM Maps

Luca Chang, Fengbin Wang, Kiernan Connolly, Hanze Meng, Zhangli Su, Virginija Cvirkaite-Krupovic, Mart Krupovic, Edward H. Egelman, Dong Si


Matter (2021)

Deterministic chaos in the self-assembly of β sheet nanotubes from an amphipathic oligopeptide

Fengbin Wang, Ordy Gnewou, Shengyuan Wang, Tomasz Osinski, Xiaobing Zuo, Edward H Egelman, Vincent P Conticello


Nat. Comm. (2021)

Structural analysis of cross α-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials

Fengbin Wang, Ordy Gnewou, Charles Modlin, Leticia C Beltran, Chunfu Xu, Zhangli Su, Puneet Juneja, Gevorg Grigoryan, Edward H Egelman, Vincent P Conticello


PNAS (2020)

Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments

Fengbin Wang, Diana P Baquero, Leticia C Beltran, Zhangli Su, Tomasz Osinski, Weili Zheng, David Prangishvili, Mart Krupovic, Edward H Egelman


Cell Rep. (2020)

Artificial intracellular filaments

Zhaoqianqi Feng, Huaimin Wang, Fengbin Wang, Younghoon Oh, Cristina Berciu, Qiang Cui, Edward H Egelman, Bing Xu


ACS nano. (2020)

Structural determination of a filamentous chaperone to fabricate electronically conductive metalloprotein nanowires

Yun X Chen, Nicole L Ing, Fengbin Wang, Dawei Xu, Nancy B Sloan, Nga T Lam, Daniel L Winter, Edward H Egelman, Allon I Hochbaum, Douglas S Clark, Dominic J Glover


Cell (2019)

Structure of microbial nanowires reveals stacked hemes that transport electrons over micrometers

Fengbin Wang, Yangqi Gu, J Patrick O’Brien, M Yi Sophia, Sibel Ebru Yalcin, Vishok Srikanth, Cong Shen, Dennis Vu, Nicole L Ing, Allon I Hochbaum, Edward H Egelman, Nikhil S Malvankar


Nat. Microbio. (2019)

An extensively glycosylated archaeal pilus survives extreme conditions

Fengbin Wang, Virginija Cvirkaite-Krupovic, Mark AB Kreutzberger, Zhangli Su, Guilherme AP de Oliveira, Tomasz Osinski, Nicholas Sherman, Frank DiMaio, Joseph S Wall, David Prangishvili, Mart Krupovic, Edward H Egelman


PNAS (2019)

A packing for A-form DNA in an icosahedral virus

Fengbin Wang, Ying Liu, Zhangli Su, Tomasz Osinski, Guilherme AP de Oliveira, James F Conway, Stefan Schouten, Mart Krupovic, David Prangishvili, Edward H Egelman


Nat Comm (2017)

A structural model of flagellar filament switching across multiple bacterial species

Fengbin Wang, Andrew M Burrage, Sandra Postel, Reece E Clark, Albina Orlova, Eric J Sundberg, Daniel B Kearns, Edward H Egelman


Structure (2017)

Cryoelectron Microscopy Reconstructions of the Pseudomonas aeruginosa and Neisseria gonorrhoeae Type IV Pili at Sub-nanometer Resolution

Fengbin Wang, Mathieu Coureuil, Tomasz Osinski, Albina Orlova, Tuba Altindal, Gaël Gesbert, Xavier Nassif, Edward H Egelman, Lisa Craig

What we do

Use cryo-EM to understand and design large assemblies

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